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pentobarbital will lower the extent or influence of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will reduce the extent or influence of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is usually a delicate CYP3A4 substrate. Coadministration

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